Effectiveness of Treatment A clinical trial tested the effectiveness of bupropion hydrochloride in helping people who want to stop smoking. Results of abstinence from smoking 52 weeks after the treatment are summarized in the table below (based on data from “A Double- Blind, Placebo-Controlled, Randomized Trial of Bupropion for Smoking Cessation in Primary Care,” by Fossatti, et al., Archives of Internal Medicine, Vol. 167, No. 16). Use a 0.05 significance level to test the claim that whether a subject smokes is independent of whether the subject was treated with bupropion hydrochloride or a placebo. Does the bupropion hydrochloride treatment appear to be better than a placebo? Is the bupropion hydrochloride treatment highly effective? 

Bupropion Hydrochloride

Placebo

Smoking

299

167

Not Smoking

101

26

 

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